产品货号：
Z14102
中文名称：
CRBN抗体
英文名称：
Anti-CRBN Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CRBN Antibody |
| 指标别名 | cereblon,CRBN,DKFZp781K0715,MRT2A,Protein cereblon |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | CRBN |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | CRBN antibody was raised against a 16 amino acid peptide near the carboxy terminus of human CRBN.The immunogen is located within the last 50 amino acids of CRBN. |
| 计算分子量 | 51kDa |
| 成分 | CRBN antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | CRBN antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | CRBN antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures. |
| 背景资料 | CRBN,a member of the Lon protease protein family,plays a role in brain development (1).It is a component of the DCX (DDB1-CUL4-X-box) E3 protein ligase complex,a complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins and is required for limb outgrowth and expression of the fibroblast growth factor FGF8 (2).CRBN is thought to regulate the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1.It is widely expressed and highly expressed in brain (3,4). |
| Uniprot ID | Q96SW2 |
| 基因名全称 | Cereblon |
| 蛋白名全称 | Cereblon |
| 推荐稀释比 | CRBN antibody can be used for detection of CRBN by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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